Source of business for IL-23 agents in psoriasis varies across biologic brands. Tremfya’s source of business includes a higher proportion of patients who have previously tried an IL-17 agent before starting an IL-23, as compared to Skyrizi. This finding suggests a preference in the market for Tremfya ahead of Skyrizi after a patient switches from an IL-17 agent.
CRA analytics insight
- A higher proportion of Tremfya patients, versus Skyrizi patients, were previously treated with an IL-17 agent (i.e., Cosentyx or Taltz) prior to trying an IL-23
- A higher proportion of Skyrizi patients were previously treated with a TNF agent compared to Tremfya patients
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